Table 1 Estimated A0, apparent diffusion co-efficient (ADC), and fractional anisotropy (FA) means and standard errors (SE) (from the linear mixed effects model) for each tissue region of interest with p-values from Dunnett’s multiple comparison with cancer, and fold difference compared with cancer.

Cancer

12405 (693)

0.002508 (0.00018)

0.1441 (0.011)

Desmoplasia

8346 (766)

p < 0.001

× 0.67

0.002736 (0.00019)

p = 0.046

× 1.09

0.3096 (0.016)

p < 0.001

× 2.15

Fibrous tissue

4646 (723)

p < 0.001

× 0.37

0.002680 (0.00019)

p = 0.026

× 1.07

0.3413 (0.013)

p < 0.001

× 2.37

Mucosa

10543 (708)

p < 0.001

× 0.85

0.002751 (0.00018)

p < 0.001

× 1.09

0.1389 (0.012)

p = 0.956

× 0.96

Submucosa

9612 (712)

p < 0.001

× 0.77

0.004567 (0.00018)

p < 0.001

× 1.82

0.1849 (0.012)

p < 0.001

× 1.28

Muscularis propria

9896 (692)

p < 0.001

× 0.80

0.002329 (0.00018)

p < 0.001

× 0.93

0.6127 (0.011)

p < 0.0001

× 4.25