Figure 6

Dose-response of tracheal epithelial cells to denatonium and saccharin. Representative calcium transients recorded from two epithelial cells stimulated with solutions containing different denatonium (a) or saccharin (c) concentrations. (b,d) Scatter dot plot and bar plot showing the normalized peak fluorescence intensity plotted versus the increasing agonist concentration. Bar plot shows mean ± sem (*P < 0.05, **P < 0.01 One sample sign test).