Table 1 Patient Demographics and Clinical Characteristics.
Variable | All patients No. of patients = 97 | Hypopharynx (H) No. of patients = 57 | Larynx (L) No. of patients = 40 | P valuea H vs. L | |
|---|---|---|---|---|---|
Age | 0.184 | ||||
Years | Median (Q25-75) | 64 (56–70.5) | 64 (58–71) | 62.5 (54–70) | |
Gender | 0.199 | ||||
Male | n (%) | 85 (87.6%) | 52 (91.2%) | 33 (82.5%) | |
Female | n (%) | 12 (12.4%) | 5 (8.8%) | 7 (17.5%) | |
Smoking | Present (%) | 94 (96.9%) | 55 (96.5%) | 39 (97.5%) | 0.778 |
Absent (%) | 3 (3.1%) | 2 (3.5%) | 1 (2.5%) | ||
Pack years | Median (Q25-75) | 40 (30–60) | 40 (20–60) | 50 (40–80) | 0.014* |
Alcohol abuse | Present (%) | 49 (50.5%) | 32 (56.1%) | 17 (42.5%) | 0.186 |
Absent (%) | 48 (49.5%) | 25 (43.9%) | 23 (57.5%) | ||
p16/ HPV PCR | Positive | 8 (8.3%) | 6 (10.5%) | 2 (5%) | 0.681 |
Negative | 37 (38.1%) | 25 (43.9%) | 12 (30%) | ||
n/a | 52 (53.6%) | 26 (45.6%) | 26 (65%) | ||
PET imaging | |||||
SUVmax primary tumor | Median (Q25-75) | 10.4 (7.4–15.7) | 12.3 (9.2–15.3) | 8.8 (6.7–16.6) | 0.062 |
TLG primary tumor | Median (Q25-75) | 34696 (18160–75166) | 42926 (21467–77672) | 29060 (15555–55644) | 0.054 |
MTV primary tumor (cm3) | Median (Q25-75) | 6.1 (3.6–8.7) | 6.1 (3.6–9.7) | 5.9 (3.5–8.2) | 0.393 |
SUVmax nodal (cN+) | Median (Q25-75) | 9.7 (7.3–11.8) | 10.8 (7.5–12.3) | 8 (6.8–10) | 0.041* |
Pharyngo-/Laryngectomy | Yes (%) | 23 (23.7%) | 14 (24.6%) | 9 (22.5%) | 0.814 |
No (%) | 74 (76.3%) | 43 (75.4%) | 31 (77.5%) | ||
T-classification | 0.99 | ||||
T1-T2 | n (%) | 40 (41.2%) | 24 (42.1%) | 16 (40%) | |
T3-T4 | n (%) | 57 (58.8%) | 33 (57.9%) | 24 (60%) | |
N-classification | <0.001* | ||||
N0 | n (%) | 36 (37.1%) | 10 (17.5%) | 26 (65%) | |
N1 | n (%) | 11 (11.3%) | 8 (14%) | 3 (7.5%) | |
N2a-b | n (%) | 29 (30%) | 23 (40.4%) | 6 (15%) | |
N2c-N3 | n (%) | 21 (21.6%) | 16 (28.1%) | 5 (12.5%) | |
