Table 1 Studied associations of CDPSs and PTs.

From: Reprogramming Escherichia coli for the production of prenylated indole diketopiperazine alkaloids

CDPS

Organism

Main produced CDP

Associated PT in this study

Name

Organism

Main activity

CDPS14

Streptomyces cattleya

cWW

AnaPT

Neosartorya fischeri

reverse prenylation at C3 of cWW (anti-cis) on one or two Trp

CdpC2PT

Neosartorya fischeri

reverse prenylation at C2 of cWW on one or two Trp

CdpC7PT

Aspergillus terreus

regular prenylation at C7 or reverse prenylation at N1 of cWW

CdpNPT

Aspergillus fumigatus

reverse prenylation at C3 of cWW (anti-cis and syn-cis)

CTrpPT

Aspergillus orizae

regular prenylation at C7 and reverse prenylation at N1 of cWW

RoqD

Penicillium chrysogenum

reverse prenylation at C3 of cWW

CDPS68

Streptomyces sp. NRRL F-5053

cWL

CdpC3PT

Neosartorya fischeri

reverse prenylation at C3 of cWL (syn-cis)

CDPS74

Streptomyces sp. NRRL S-1868

cWP

BrePT

Aspergillus versicolor

reverse prenylation at C2 of cWP

EchPT1

Aspergillus ruber

reverse prenylation at C2 of cWP

FtmPT1

Aspergillus fumigatus

regular prenylation at C2 of cWP

NotF

Aspergillus sp.

reverse prenylation at C2 of cWP

  1. Data for CDPS1429 and CDPS68 and CDPS7428 were previously published.
  2. Data for PT activities were taken from published studies: AnaPT37, CdpC2PT43, CdpC3PT38, CdpC7PT44, CdpNPT39,40, CTrpPT45, RoqD41,42, BrePT34, EchPT135, FtmPT146 and NotF36; anti-cis and syn-cis refers to the stereochemistry of prenylation at C3.