Figure 3
From: Loss of MafA and MafB expression promotes islet inflammation
Islet inflammation in 6 months MafA−/−MafB+/− pancreata. Inflammatory immune cells were characterized with the following markers on adjacent cryopreserved pancreatic sections: (A–H) Nucleus (DAPI; grey), insulin (green), (A) CD4 (red), (B) CD8 (red), (C) dendritic cell marker CD205 (red), (D) macrophage/monocyte CD11b (red), (E–F) T cell marker CD3 (red), B cell marker B220 (blue) and (F) proliferation marker Ki67 (blue). (G,H) CD3+ and CD45+ immune cells within islets. (E–H) Arrows point to cells magnified in inserts and scale bar is 40 µm.
