Figure 1
From: SOCS2 is part of a highly prognostic 4-gene signature in AML and promotes disease aggressiveness
Prognostic value of the 4-GES in 162 cytogenetically normal AML patients (GSE12417, cohort 1). (A) Cut-off value for stratification of AML patients into 4-GESlow (blue) and 4-GEShigh (red) was calculated by maximally selected rank statistics. (B) Kaplan Meier curves for overall survival of 162 AML patients classified as 4-GESlow or 4-GEShigh. Log rank tests were calculated and p-values were adjusted for multiple testing according to Altman et al.58. (C) Heatmap summarizing expression values of SOCS2, IL2RA, NPDC1 and PHGDH in 4-GESlow (blue) and 4-GEShigh (red) AML patients. Blue, low expression; red, high expression.
