Figure 5

Altered glucose homeostasis and fat deposition in Lactobacillus treated WT animals. (a) Absolute quantification of the genus Lactobacillus by qPCR in the small intestine (SI), caecum and faeces of P2rx7−/− (yellow) and WT (blue) mice. (b) Glycaemia after 21 days of treatment. (c) Fat deposition as measured by perigonadal white adipose tissue weight. (d) Glucose tolerance test (GTT). (e) Areas under the curve (AUC) of GTT. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001, Wilcoxon rank-sum test; n = 10 per group; n = 7 for GTT of L. murinus group.