Table 3 Summary of Methyltransferase genes from the chromosomes of 95JB1 and 95NR1.

From: SMRT sequencing reveals differential patterns of methylation in two O111:H- STEC isolates from a hemolytic uremic syndrome outbreak in Australia

MTase

Type1

95JB1 Enzyme name

95NR1 Enzyme name

Predicted Specificity2

Homolog1 (% aa similarity)

I

II

M.Eco95JB1I

M.Eco95NR1I

nonspecific

M.EcoGI/GII (92.8/92.4)

II

II

M.Eco95JB1II

M.Eco95NR1II

nonspecific

M.EcoGI/GII (93.6/93.1)

Dcm

II

M.Eco95JB1Dcm

M.Eco95NR1Dcm

CCWGG

M.EcoGDcm (98.5)

III

II

M.Eco95JB1III

M.Eco95NR1III

CTGCAG

M.EcoGIII (99.7)

IV

II

M.Eco95JB1IV

M.Eco95NR1IV

GATC

M.EcoGV (99.6)

V

II

M.Eco95JB1V

M.Eco95NR1V

ATGCAT

M.EcoGVI (98.6)

Dam

II

M.Eco95JB1Dam

M.Eco95NR1Dam

GATC

M.EcoGDam (99.7)

VI

II

—

M.Eco95NR1VI

GATC

M.EcoGV (99.4)

VII

II

—

M.Eco95NR1VII

GATC

M.EcoVT2 (99.2)

VIII

II

—

M.Eco95NR1VIII

GATC

M.EcoVT2 (99.2)

IX

IIG4

Eco95JB1IX

Eco95NR1IX

CRARCAG3

SenTFIV (76)

X

II

M.Eco95JB1X

M.Eco95NR1X

SAY

M.EcoGIX (96)

  1. 1Methyltransferases were classified based on similarity searches with the REBASE database19.
  2. 2Specificities only included if determined by PacBio.
  3. 3Predicted recognition motif based on the in silico bioinformatic characterisation of all MTase in 95JB1 and 95NR1 (this study).
  4. 4Type IIG enzymes are bifunctional with both REase and MTase capabilities19.
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