Figure 6 | Scientific Reports

Figure 6

From: Wnt signalling mediates miR-133a nuclear re-localization for the transcriptional control of Dnmt3b in cardiac cells

Figure 6

The AGO2/miR-133a complex binds to the Dnmt3b promoter and induces epigenetic changes associated with transcriptional repression. (A–C) ChIP assay evaluating the enrichment of AGO2, H3K27me3, and H3K4me3 in the proximity of PBSM in the Dnmt3b promoter. Representative experiments are shown (n = 3); *p < 0.05; **p < 0.01; ***p < 0.001.

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