Figure 4
From: Vertebrates originally possess four functional subtypes of G protein-coupled melatonin receptor
Concentration-response curve of typical MTNR antagonist for medaka MTNRs with EC90 melatonin. Y-axis shows antagonistic index (AI) and the x-axis shows the concentration of reagents used for cell treatments. The upper gray box signifies the mean ± standard error of the mean (S.E.M.) value of forskolin (FSK) and the lower gray box represents the average (±S.E.M.) value of the 90% effective concentration of melatonin (MTN). Each point represents the mean of triplicate calculations, and vertical bars represent the S.E.M.
