Figure 2
From: Characterisation of the Selective Reduced Uteroplacental Perfusion (sRUPP) Model of Preeclampsia
Mean arterial blood pressure recordings following instrumentation with telemetric TA11PA-C10 probes on GD5-7. (A) Data averaged over 12-hour intervals from GD7-21. Yellow bands indicate periods of analgesia medication. Blue band indicates period spent in a metabolic cage for urine collection. MAP was significantly elevated on GD17.5 and 18.5 following surgery on GD14. (B) Data for GD17-20 averaged over 1-hour intervals and plotted to display 24-hour cycles. In the Sham group MAP remained at around the level seen during daylight/inactive hours throughout the 24-hour period. In both RUPP and sRUPP groups, MAP was generally higher compared to SHAMs and found to be significantly different during night/active hours. Data analysed by two-way ANOVA with Sidak’s post hoc test; *p < 0.05 vs. Sham group.
