Table 2 Cytokine levels in plasma from Sham, RUPP and sRUPP groups on GD21. Data are presented as mean (range) and analysed by the Kruskal-Wallis test for non-parametric data.
From: Characterisation of the Selective Reduced Uteroplacental Perfusion (sRUPP) Model of Preeclampsia
Sham, n = 5 | RUPP, n = 5 | sRUPP, n = 5 | Kruskal-Wallis test | |
|---|---|---|---|---|
Pro-inflammatory | ||||
IFN-γ (pg/ml) | 582 (367–1121) | 481 (59–808) | 659 (240–1260) | |
IL-1α (pg/ml) | 119 (63–208) | 180 (116–197) | 136 (102–318) | |
IL-1β (pg/ml) | 28 (9–41) | 25 (12–49) | 38 (11–68) | p = 0.0931 |
IL-17 (pg/ml) | 78 (49–91) | 85 (70–93) | 83 (53–130) | |
TNF-α (pg/ml) | 9 (6–11) | 8 (6–10) | 6 (6–11) | |
RANTES (pg/ml) | 246 (73–320) | 513 (318–1427) | 657 (255–1703) | * |
MCP-1 (pg/ml) | 379 (213–515) | 382 (131–413) | 291 (253–574) | |
Pro- and anti-inflammatory | ||||
IL-6 (pg/ml) | 212 (77–629) | 224 (154–309) | 350 (131–466) | |
Anti-inflammatory | ||||
IL-10 (pg/ml) | 104 (36–203) | 84 (10–143) | 56 (2–143) | |
Angiogenesis | ||||
VEGF (pg/ml) | 106 (60–126) | 123 (79–182) | 85 (56–174) | |
sFlt (ng/ml) | 1.26 (0.76–2.65) | 0.93 (0.56–2.14) | 0.93 (0.65–2.00) | |
PlGF (pg/ml) | 0.29 (0.14–0.85) | 0.10 (0.04–0.98) | 0.19 (0.09–0.75) | |
Endoglin (ng/ml) | 0.84 (0.65–1.21) | 0.59 (0.35–1.10) | 0.69 (0.40–0.76) | * |
