Table 3 Adjusted relative risks (RR) with 95% confidence intervals (CI) for the association between obesity, comorbidities and adverse labor and neonatal outcomes in singleton deliveries of women between 2005 and 2016 (n = 324,664).

From: Adverse perinatal outcomes for obese women are influenced by the presence of comorbid diabetes and hypertensive disorders

 

aRRa (95% CI)

total obese

non-obese comorbid

obese non-comorbid

obese comorbid

Comorbidities

Hypertensive disorders

4.01 (3.81,4.22)

   

Pre-existing diabetes

3.83 (3.48,4.20)

   

Gestational diabetes mellitus (GDM)

3.24 (3.11,3.36)

   

Labor outcomes

Cesarean section

1.55 (1.52,1.58)

1.41 (1.37,1.44)

1.52 (1.48,1.56)

1.84 (1.76,1.91)

Epidural anesthesia

1.05 (1.02,1.07)

1.01 (0.98,1.04)

1.07 (1.04,1.10)

0.99 (0.93,1.04)

Failure to progress in labor

1.48 (1.42,1.54)

0.94 (0.89,0.99)

1.54 (1.47,1.61)

1.25 (1.13,1.37)

Fetal heart rate anomaly

1.09 (1.06,1.12)

1.06 (1.03,1.09)

1.12 (1.09,1.15)

1.01 (0.95,1.07)

Induction of labor

1.65 (1.60,1.69)

2.06 (2.01,2.11)

1.54 (1.49,1.59)

2.60 (2.49,2.71)

Instrumental vaginal delivery

1.06 (1.02,1.11)

1.02 (0.98,1.07)

1.07 (1.02,1.12)

1.02 (0.93,1.13)

Prolonged labor

1.04 (1.00,1.09)

0.86 (0.82,0.91)

1.07 (1.02,1.13)

0.89 (0.81,0.91)

Shoulder dystocia

1.69 (1.46,1.95)

1.74 (1.49,2.01)

1.53 (1.29,1.80)

2.78 (2.14,3.55)

Neonatal outcomes

5′ Apgar score ≤7

1.17 (1.11,1.23)

1.40 (1.33,1.45)

1.08 (1.02,1.15)

1.60 (1.46,1.75)

Early neonatal death

1.08 (0.88,1.31)

1.30 (1.06,1.57)

0.94 (0.73,1.18)

1.68 (1.19,2.29)

Fracture of the clavicle

1.61 (1.20,2.12)

1.06 (0.72,1.51)

1.65 (1.20,2.23)

1.47 (0.70,2.67)

Intensive care unit admission

1.22 (1.16,1.29)

2.03 (1.93,2.13)

1.08 (1.01,1.16)

2.10 (1.92,2.29)

Macrosomia

1.93 (1.86,2.00)

1.11 (1.05,1.16)

1.96 (1.89,2.04)

1.84 (1.70,1.99)

Neonatal hypoglycemia (<2 mmol/L)

1.64 (1.45,1.86)

4.28 (3.88,4.71)

1.26 (1.05,1.49)

4.63 (3.91,5.44)

Preterm birth (<37 weeks of gestation)

0.99 (0.94,1.05)

2.34 (2.26,2.44)

0.81 (0.76,0.87)

2.03 (1.88,2.20)

Respiratory distress of newborn

1.34 (1.27,1.41)

1.79 (1.70,1.89)

1.23 (1.15,1.32)

2.03 (1.85,2.23)

  1. aPoisson (prevalence >10%) or logistic (prevalence <10%) models adjusted for age, ethnicity, parity and history of smoking during pregnancy. Additionally adjusted for cesarean delivery.