Table 3 Adjusted relative risks (RR) with 95% confidence intervals (CI) for the association between obesity, comorbidities and adverse labor and neonatal outcomes in singleton deliveries of women between 2005 and 2016 (n = 324,664).
aRRa (95% CI) | ||||
---|---|---|---|---|
total obese | non-obese comorbid | obese non-comorbid | obese comorbid | |
Comorbidities | ||||
Hypertensive disorders | 4.01 (3.81,4.22) | |||
Pre-existing diabetes | 3.83 (3.48,4.20) | |||
Gestational diabetes mellitus (GDM) | 3.24 (3.11,3.36) | |||
Labor outcomes | ||||
Cesarean section | 1.55 (1.52,1.58) | 1.41 (1.37,1.44) | 1.52 (1.48,1.56) | 1.84 (1.76,1.91) |
Epidural anesthesia | 1.05 (1.02,1.07) | 1.01 (0.98,1.04) | 1.07 (1.04,1.10) | 0.99 (0.93,1.04) |
Failure to progress in labor | 1.48 (1.42,1.54) | 0.94 (0.89,0.99) | 1.54 (1.47,1.61) | 1.25 (1.13,1.37) |
Fetal heart rate anomaly | 1.09 (1.06,1.12) | 1.06 (1.03,1.09) | 1.12 (1.09,1.15) | 1.01 (0.95,1.07) |
Induction of labor | 1.65 (1.60,1.69) | 2.06 (2.01,2.11) | 1.54 (1.49,1.59) | 2.60 (2.49,2.71) |
Instrumental vaginal delivery‡ | 1.06 (1.02,1.11) | 1.02 (0.98,1.07) | 1.07 (1.02,1.12) | 1.02 (0.93,1.13) |
Prolonged labor | 1.04 (1.00,1.09) | 0.86 (0.82,0.91) | 1.07 (1.02,1.13) | 0.89 (0.81,0.91) |
Shoulder dystocia | 1.69 (1.46,1.95) | 1.74 (1.49,2.01) | 1.53 (1.29,1.80) | 2.78 (2.14,3.55) |
Neonatal outcomes | ||||
5′ Apgar score ≤7 | 1.17 (1.11,1.23) | 1.40 (1.33,1.45) | 1.08 (1.02,1.15) | 1.60 (1.46,1.75) |
Early neonatal death | 1.08 (0.88,1.31) | 1.30 (1.06,1.57) | 0.94 (0.73,1.18) | 1.68 (1.19,2.29) |
Fracture of the clavicle | 1.61 (1.20,2.12) | 1.06 (0.72,1.51) | 1.65 (1.20,2.23) | 1.47 (0.70,2.67) |
Intensive care unit admission | 1.22 (1.16,1.29) | 2.03 (1.93,2.13) | 1.08 (1.01,1.16) | 2.10 (1.92,2.29) |
Macrosomia | 1.93 (1.86,2.00) | 1.11 (1.05,1.16) | 1.96 (1.89,2.04) | 1.84 (1.70,1.99) |
Neonatal hypoglycemia (<2 mmol/L) | 1.64 (1.45,1.86) | 4.28 (3.88,4.71) | 1.26 (1.05,1.49) | 4.63 (3.91,5.44) |
Preterm birth (<37 weeks of gestation) | 0.99 (0.94,1.05) | 2.34 (2.26,2.44) | 0.81 (0.76,0.87) | 2.03 (1.88,2.20) |
Respiratory distress of newborn | 1.34 (1.27,1.41) | 1.79 (1.70,1.89) | 1.23 (1.15,1.32) | 2.03 (1.85,2.23) |