Table 4 Attributable Fraction in the population (AFp) with 95% confidence intervals (CI) for the risk factors with a variable combining obesity and comorbidities.

From: Adverse perinatal outcomes for obese women are influenced by the presence of comorbid diabetes and hypertensive disorders

 

AFpa [%] (95% CI)

total obese

non-obese comorbid

obese non-comorbid

obese comorbid

Comorbidities

Hypertensive disorders

15.4 (14.5,16.4)

   

Pre-existing diabetes

15.0 (13.3,16.7)

   

Gestational diabetes mellitus (GDM)

13.2 (12.6,13.8)

   

Labor outcomes

Cesarean section

3.8 (3.6,3.9)

2.4 (2.3,2.6)

2.9 (2.7,3.0)

1.3 (1.2,1.4)

Epidural anesthesia

0.6 (0.5,0.8)

0.2 (0.1,0.4)

0.6 (0.4,0.7)

0.1 (0.0,0.1)

Failure to progress in labor

1.1 (0.8,1.4)

−1.5 (−1.7,−1.2)

1.2 (0.9,1.5)

−0.2 (−0.3,−0.1)

Fetal heart rate anomaly

0.7 (0.6,0.9)

0.4 (0.3,0.6)

0.7 (0.6,0.9)

0.0 (0.0,0.1)

Induction of labor

4.5 (4.2,4.7)

6.1 (5.9,6.4)

3.0 (2.8,3.2)

2.4 (2.3,2.6)

Instrumental vaginal delivery

0.4 (0.1,0.7)

0.1 (−0.1,0.4)

0.4 (0.1,0.6)

0.0 (0.0,0.2)

Prolonged labor

0.8 (0.5,1.2)

−0.5 (−0.8,−0.3)

0.8 (0.5,1.1)

0.0 (−0.2,0.1)

Shoulder dystocia

4.8 (3.2,6.2)

4.3 (2.9,5.8)

2.9 (1.6,4.3)

2.7 (1.7,3.8)

Neonatal outcomes

5′ Apgar score ≤7

1.2 (0.7,1.6)

2.4 (2.0,2.8)

0.5 (0.1,0.8)

0.9 (0.7,1.2)

Early neonatal death

1.0 (−0.2,2.4)

1.8 (0.2,3.3)

−0.4 (−1.7,0.9)

1.1 (0.2,1.9)

Fracture of the clavicle

4.3 (1.8,7.4)

0.4 (−2.1,2.8)

3.6 (0.8,6.3)

0.7 (−0.8,2.2)

Intensive care unit admission

1.6 (1.2,2.0)

5.9 (5.4,6.5)

0.5 (0.0,0.9)

1.7 (1.4,2.0)

Macrosomia

6.3 (5.9,6.7)

0.6 (0.3,1.0)

5.2 (4.8,5.5)

1.3 (1.1,1.5)

Neonatal hypoglycemia (<2 mmol/L)

4.5 (3.1,5.7)

16.8 (15.0,18.6)

1.4 (0.2,2.6)

5.4 (4.3,6.5)

Preterm birth (<37 weeks of gestation)

0.0 (−0.4,0.3)

7.7 (7.2,8.2)

−1.1 (−1.4,−0.7)

1.6 (1.3,1.8)

Respiratory distress of newborn

2.4 (1.9,2.8)

4.6 (4.2,5.2)

1.3 (0.8,1.7)

1.6 (1.3,1.9)

  1. aAttributable fraction in the population adjusted for age, ethnicity, parity and history of smoking during pregnancy. Additionally adjusted for cesarean delivery.