Table 1 Gene expression changes in colorectal carcinoma as compared to normal tissue in our cohort and similarly in 2 TCGA cohorts.

From: Radiogenomics-based cancer prognosis in colorectal cancer

Gene Symbol

Our cohort

TCGA-Microarray

TCGA-RNAseq

Mean

SEM

Mean

SEM

p adj*

Mean

SEM

p adj*

ABCB1

0.451

0.05

0.332

0.021

<0.0001

0.447

0.026

<0.0001

ABCC2

4.211

1.03

3.45

0.333

<0.0005

16.625

1.69

<0.0001

ABCG2

0.113

0.01

0.074

0.008

<0.0001

0.05

0.005

<0.0001

ALDH1A1

0.667

0.08

0.579

0.043

<0.0001

0.574

0.044

<0.0001

CD166 (ALCAM)

1.722

0.12

1.89

0.086

<0.0001

1.955

0.057

<0.0001

CDKN1A

0.592

0.04

0.584

0.023

<0.0001

0.457

0.017

<0.0001

INHBB

1.599

0.23

4.217

0.533

<0.0001

6.88

0.645

<0.0001

  1. *Comparison of CRC versus NT (Normal Tissues) was performed by Welch’s t-test and p values for TCGA data were corrected for multiple testing by Benjamini-Hochberg method (p.adjust function in R environment). SEM - Standard error of the mean.
Back to article page