Figure 5
From: Distribution of fitness effects of mutations obtained from a simple genetic regulatory network model
DFE of deleterious mutations cannot be represented by any standard distribution for all three initial fitness. System is simulated for 0.01fmax, 0.1fmax and 0.5fmax with 100 different parameter sets (80 parameter sets for 0.5fmax). DFE of deleterious mutations associated with all three fitness levels cannot be represented any standard distribution. The fitting parameter λ and goodness of fit \({R}^{2}\) associated with each parameter sets are plotted. We see that the overall quality of fit to exponential distribution is poor for all three initial fitness. In addition, we also note that for many parameters deleterious frequency distribution have two-peak (inset).
