Figure 7
From: Distribution of fitness effects of mutations obtained from a simple genetic regulatory network model
Magnitude of fitness effect of beneficial mutations decrease with increasing fitness. We plot the ratio between the differences in fitness, when the same mutation is acquired alone by one parameter set (Δf) versus when in conjunction with another beneficial mutation in another parameter (Δf*) (Y-axis), across different parameter sets arranged in the increasing order of their fitness (X-axis). The parameter sets are generated the same way as discussed for Fig. 6. (A) refers to the sets when the beneficial mutation is introduced in parameter p1 and the sets on the X-axis are carrying a beneficial mutation in a parameter other than p1. (B–E) refer to sets when the beneficial mutation is introduced in parameters p2, p3, p4, and p5. Parameters p1, p2, p3, p4, and p5 are the same as described before.
