Figure 3 | Scientific Reports

Figure 3

From: Acute and short-term administrations of delta-9-tetrahydrocannabinol modulate major gut metabolomic regulatory pathways in C57BL/6 mice

Figure 3

Fecal metabolome changes in 5X samples. (a) Volcano plots showing the metabolites with differential abundance between THC treated mice and the controls. These were selected based on fold change (X-axis) and p-value in (Y-axis). The m/z values (highlighted in pink) represent a fold change of ≥0.5 or ≤2.0 and p-value ≤ 0.05 in THC administered mice compared to the vehicle controls and were selected for further characterization. (b) PCA score scatter plots based on fecal metabolic profiling of THC (n = 5) and control (n = 5) mice c) PLS- DA score plots based on detected fecal metabolites from THC administered (n = 5) and control (n = 5) mice. T, THC administered mice, C, control mice.

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