Figure 2

(A–F) Legend: Association between cytokines plasma levels, BMI and degree of synovial inflammation in naïve RA patients and in RA patients in stable clinical and ultrasound remission. (A) IL-1RA plasma levels in naïve to treatment RA patients based on the BMI category, *p = 0.002; (B) IL-1RA plasma levels in naïve to treatment RA based on the BMI category and synovitis pattern, *p = 0.05 and **p = 0.04; (C) Correlation between IL-1RA plasma levels and BMI value in naïve to treatment RA patients; (D) Correlation between IL-1RA plasma levels and DAS value in naïve to treatment RA patients; (E) Correlations between IL-6 plasma levels and lining IHC scores for CD68⁺, CD3⁺ and CD20⁺ cells in naïve to treatment RA patients and RA patients in stable clinical and ultrasound remission; (F) Correlations between IL-6 plasma levels and sublining IHC scores for CD68⁺, CD21⁺, CD3⁺ and CD20⁺ cells in naïve to treatment RA patients and RA in stable clinical and ultrasound remission; RA: Rheumatoid Arthritis; BMI: Body Mass Index; IHC: Immunohistochemistry; CD: Cluster Designation.