Table 1 Select non-synonymous mutations in resistant cells discovered by RNA sequencing.
From: Heterozygous mutations in valosin-containing protein (VCP) and resistance to VCP inhibitors
Gene | Reference | Substitution | Zygosity |
|---|---|---|---|
VCP | E470 | K | Heterozygous |
VCP | E470 | D | Heterozygous |
FLNA | R484 | W | Heterozygous |
UQCR10 | S8 | L | Heterozygous |
MCM7 | A241 | S | Heterozygous |
APBB2 | T131 | S | Homozygous |
TNKS1BP1 | P602 | H | Heterozygous |
ADAM10 | I385 | F | Heterozygous |
SLC16A3 | D260 | A | Heterozygous |
TRAK1 | N857 | S | Heterozygous |
ATG4B | V364 | D | Heterozygous |
