Table 2 Molecular volume of biomolecules and helium under different experimental conditions. % change, calculated with respect to 1 bar. Helium DOPC “bubble” refers to helium confined between the two monolayers.

From: The effect of high pressure on the NMDA receptor: molecular dynamics simulations

Experiment

DOPC (nm³)

DOPC % change

NMDAR (nm³)

NMDAR % change

Helium DOPC “bubble” (nm³)

1 bar

585.6

 

489

  

25 bar

586.6

0.17

487.8

−0.25

 

Helium 25 bar

582

−0.61

489.3

0.07

396.6