Table 4 List of circRNAs selected for validation with their corresponding parental gene, MREs, miRNAs, and associated miRNA function.

From: Circular RNAs are differentially expressed in prostate cancer and are potentially associated with resistance to enzalutamide

CircRNA

Genomic Location

Expression

Fold Change

p-value

Parental Gene

MRE

Gene Function

hsa_circ_0004870

chr20:34302106-34313077

down

2.4

0.0015

RBM39

miR-145

Cancer cell migration and invasion50

hsa_circ_0002807

chr13:114149816-114164739

down

1.7

0.0009

TMCO3

miR-141

Suppresses stem cells51

hsa_circ_0022383

chr11:61605249-61615756

down

6.1

0.0244

FADS2

miR-124

Inhibits invasion and proliferation52

hsa_circ_0003505

chr17:20910208-20911309

down

1.6

0.0421

USP22

miR-124

Inhibits invasion and proliferation52

hsa_circ_0088059

chr9:114905750-114905903

down

2.5

0.0281

SUSD1

miR-124

Inhibits invasion and proliferation52

hsa_circ_0000673

chr16:11940357-11940700

up

3.5

0.0053

RSL1D1

miR-25

Modulates invasiveness and dissemination53

hsa_circ_0002754

chr8:41905895-41907225

up

2.3

0.0493

KAT6A

miR-145

Cancer cell migration and invasion53,54,55

hsa_circ_0001278

chr3:31617887-31621588

up

1.6

0.0004

STT3B

miR-205

ERG target gene56

hsa_circ_0001721

chr7:90355880-90356126

up

1.9

0.0103

CDK14

miR-221

Promotes cell proliferation and represses apoptosis35

hsa_circ_0083092

chr7:155471301-155473602

up

2.4

0.0051

RBM33

miR-125b

Tumour suppressor57