Figure 4
From: VEGF mediates fat embolism-induced acute lung injury via VEGF receptor 2 and the MAPK cascade
Effects of SU1498 on the pulmonary phosphorylation of Raf (p-Raf), MEK (p-MEK), and ERK (p-ERK) in sham rats (sham), rats with vehicle (vehicle), rats with fat embolism (FE), or rats treated with SU1498 (FE + SU1498). Left: western blot analysis of sham rats (sham), rats with vehicle (vehicle), rats with fat embolism (FE), or rats treated with SU1498 (FE + SU1498); Right: Relative density presented as percent increase compared with sham group. Data are represented as the mean ± SEM values (n = 5). **p < 0.01 was considered significantly different from sham values, and #p < 0.05 was considered significantly different from rats with FE treatment by the Mann–Whitney U-test.
