Table 1 Sensitivity, specificity, and positive and negative predictive values of Xpert, AFB smear and MGIT 960 in detecting UTB from urine specimens.

From: Multicentre evaluation of Xpert MTB/RIF assay in detecting urinary tract tuberculosis with urine samples

Gold standard

Screening method

Test performance

Sensitivity (95% CI)

Specificity (95% CI)

PPV (95% CI)

NPV (95% CI)

MGIT 960 culture

Xpert

94.4% (34/36)

89.5% (238/266)

54.8% (34/62)

99.2% (238/240)

(81.3–99.3%)

(85.1–92.9%)

(41.7–67.5%)

(97.0–99.9%)

AFB smear

22.2% (8/36)

97.7% (260/266)

57.1% (8/14)

90.3% (260/288)

(10.1–39.2%)

(95.2–99.2%)

(28.9–82.3%)

(86.3–93.4%)

CRS

Xpert

41.3% (62/150)

100% (152/152)

100% (62/62)

63.3% (152/240)

(33.4–49.7%)

—

—

(56.9–69.4%)

AFB smear

7.3% (11/150)

98.0% (149/152)

78.6% (11/14)

51.7% (149/288)

(3.7–12.7%)

(94.3–99.6%)

(49.2–95.3%)

(45.8–57.6%)

MGIT 960

24.0% (36/150)

100% (152/152)

100% (36/36)

57.1% (152/266)

(17.4–31.6%)

—

—

(51.0–63.2%)

  1. CI, confidence interval; PPV, positive predictive value; NPV, negative predictive value.
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