Figure 2
From: Deregulation of TLR4 signaling pathway characterizes Bicuspid Aortic valve syndrome

Expression levels of genes encoding inflammatory cytokines. The figure reports the gene expression levels of IL-1β, IL-6 and IL-7 in normal or aneurysmatic tissue samples from 51 BAV and 25 TAV cases with AAA. The comparison of data of each cytokine gene detected significant differences among the four groups with p < 0.0001, by ANOVA test, Bonferroni corrected, and between normal and aneurysmatic aorta tissues from BAV and TAV cases (p = 0.0001, by t test, Welch corrected), with the lowest peaks in all the aorta tissues from BAV cases. The statistical significance was detected by using t test and ANOVA test, when appropriate.