Table 2 Demographic and clinical characteristics, comorbodity conditions, complications of 70 BAV and 70 TAV subjects.

From: Deregulation of TLR4 signaling pathway characterizes Bicuspid Aortic valve syndrome

Variables

BAV N = 70

TAV N = 70

P

Demographic characteristics

Age, mean (SD)

58.8 (14.8)

69.1(12.8)

<0.0001

Male sex, No. (%)*

50 (71)

35(50)

0.009

Female sex, No. (%)

20 (29)

35 (50)

0.009

Body mass index, mean (SD)

26 (4.8)

26.3 (3.2)

N.S.

Size and location of AAA

Subjects affected (%)

51 (73)

25(36)

0.00001

Size (mm), mean (SD)

53.3 (7.4)

50.3 (6.9)

N.S.

Location, No:

   

Tubular ascending aorta

51 (100)

25 (100)

N.S.

Comorbidity conditions, No (%)

CVD Family History

8 (11)

5 (7.1)

N.S.

Smoking

26 (37)

20 (28)

N.S.

Hypertension

55 (78)

50 (719

N.S.

Dyslipidemia

9 (13)

5 (7.1)

N.S.

Diabetes mellitus

3 (4.2)

1 (1.4)

N.S.

Renal failure

0 (0)

1 (1.4)

N.S.

Dissection

0 (0)

0 (0)

N.S.

Aortic valve pathology, No (%):

 

Normal

0 (0)

38 (54)

0.0001

 

Prolapse

8 (11)

0(0)

0.003

 

Vascular calcium fibrosis

35 (50)

7 (10)

2.4e-7

Atherosclerosis coronary syndrome, No (%):

 

2 (3)

1 (0.8)

N.S.

  1. *Percentage values on total BAV and TAV subjects.
  2. P = TAV vs. BAV, by t Student test for quantitative variables, or χ2 test for qualitative variables.