Figure 6 | Scientific Reports

Figure 6

From: A small molecule inhibitor of ER-to-cytosol protein dislocation exhibits anti-dengue and anti-Zika virus activity

Figure 6

CP26 inhibits the activity of cholera toxin but not ricin. (A) CP26 inhibits cholera toxin-induced increases in cAMP in HeLa cells. Data shown are the mean ± SEM, n = 3, p < 0.0001 vs. cholera toxin alone by ANOVA. (B, C) CP26 does not affect ricin cytotoxicity. (B) HeLa cell confluence was recorded in real time and quantified from 0 to 3 days (mean ± SEM, n = 3). (C) qPCR analysis of ricin-induced depurination (mean ± SEM, n = 3). n.s.: no significant difference.

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