Figure 5
From: Concentric lamellae – novel microanatomical structures in the articular calcified cartilage of mice
Measurements of concentric lamellae in BALB/c AKU and WT mice. (a) Quantification of the lamella in a 7.8 week old AKU mouse showed a general increase in width as they progressed further away from the chondrocyte (x16,500). (b,c) The number of lamellae surrounding chondrocytes in aged AKU mice (53 + 61 weeks old respectively) increased in comparison to young AKU mice (a), however the widths of the lamellae were significantly narrower (x26,500). (d) Quantification of the lamellae in an aged WT mouse (69 weeks) revealed the number of lamellae was comparable to that seen in young AKU mice (a), whilst the width was comparable to that seen in aged AKU mice (b,c) (x4200). Tissues fixed in (a,b) glutaraldehyde (c,d) PBFS. Scale = (a–c) 1 µm, (d) 5 µm.
