Table 2 List of most significant upregulated and downregulated genes in septic shock.

From: Differential gene expression analysis reveals novel genes and pathways in pediatric septic shock patients

Gene

Fold Change

Average Expression

t-statistics

p-value

adj. p-value

Reference

DDIT4

2.12

8.441545

5.490723

1.33E-07

0.000592

26,49

CCL3

2.12

6.208106

4.627029

7.02E-06

0.012717

29

PRG2

2.11

5.48492

5.611777

7.35E-08

0.000533

—

MT1M

1.78

3.72997

5.641576

6.35E-08

0.000533

—

CDC20

1.68

6.18643

4.059008

7.31E-05

0.040893

25

KIF20A

1.66

4.940242

4.673723

5.74E-06

0.012717

—

MAFF

1.64

6.815799

4.437113

1.58E-05

0.015559

50

EBI3

1.64

5.41593

4.517058

1.12E-05

0.013575

51

MELK

1.63

6.413027

4.141523

5.27E-05

0.034718

—

TOP2A

1.58

4.997892

4.045113

7.72E-05

0.040893

52

NUSAP1

1.54

6.627514

3.928091

0.000121

0.049772

53

RGL1

1.52

7.288761

4.447937

1.51E-05

0.015559

54

ARHGEF40

−1.66

6.880613

−3.994983

9.38E-05

0.043368

—

LOC254896

−1.65

8.498379

−4.452352

1.48E-05

0.015558

—

SLC46A2

−1.61

5.880150

−4.084894

6.60E-05

0.039833

—

TNFRSF10C

−1.54

8.678817

−4.643272

6.55E-06

0.012717

55