Figure 7
From: SPECTRUM – A MATLAB Toolbox for Proteoform Identification from Top-Down Proteomics Data
Spectral generation and comparisons workflow and contextual explanation. (a) After retrieving protein sequences from user-selected protein database, theoretical fragments of each protein are generated. Experimental and theoretical spectra are then compared to get in silico component score. (b) Step 1: Obtain experimental spectrum, Step 2: Generate theoretical fragments of candidate protein, Step 3: Experimental and theoretical spectra are compared to get number of matches, and Step 4: In silico component score is computed.
