Figure 3
From: Short-term CFTR inhibition reduces islet area in C57BL/6 mice
Islet hormone concentrations. Peripheral plasma concentrations of (a) insulin (n = 10–15), (c) glucagon (n = 6–8), and (e) GLP-1 (n = 5–8) were assessed on Day 12 of the study. Additionally, the pancreatic content of (b) insulin (n = 6–8), (d) glucagon (n = 7–8), and (f) GLP-1 (n = 5) were assessed in protein extracted from pancreatic tissue. All observations were made in mice fasted for 2 hours. Data are presented as mean ± SEM for a given number of mice (n) as indicated above. *p < 0.05, **p < 0.01 and ***p < 0.001 compared to control animals (One-way ANOVA).
