Table 2 Changes in physical, biochemical and ultrasonic parameters after 8-weeks of intervention.

From: A Randomised Controlled Trial on the Effectiveness and Adherence of Modified Alternate-day Calorie Restriction in Improving Activity of Non-Alcoholic Fatty Liver Disease

Variables

Control Group (Mean)a

MACR Group (Mean)a

*p-value

Mean differencec (95% CI)

Within-groupb

Between-groupc

Pre

Post

Pre

Post

Control

MACR

Weight (kg)

77.66

78.55

80.80

78.79

0.86

0.003

0.001

3.06 (1.14 to 4.63)

BMI (kg/m2)

27.86

28.17

31.73

30.95

0.12

0.003

0.02

1.08 (0.16 to 2.00)

ALT (IU/L)

96.78

90.22

84.33

59.17

0.32

0.001

0.02

18.61(−0.10 to 37.23)

AST (IU/L)

54.22

50.89

51.40

42.77

0.45

0.004

0.34

5.3 (−5.99 to 16.59)

TC (mmol/L)

5.09

5.36

5.32

5.28

0.42

0.78

0.34

0.31 (−0.35 to 0.96)

LDL (mmol/L)

3.19

3.28

3.35

3.36

0.76

0.92

0.75

0.08 (−0.42 to 0.59)

HDL (mmol/L)

1.04

1.11

1.15

1.11

0.31

0.28

1.16

0.12 (−0.05 to 0.29)

TG (mmol/L)

2.02

2.12

1.97

2.09

0.51

0.58

0.97

−0.13 (−0.83 to 0.80)

FBS (mmol/L)

6.85

5.93

6.62

5.87

0.08

0.006

0.74

−0.17 (−1.24 to 0.88)

Liver steatosis

2.00

1.89

1.93

1.43

0.34

0.001

0.01

0.38 (−0.02 to 0.79)

SWE (kPa)

6.57

6.45

5.87

5.01

0.56

0.001

0.01

0.74 (0.19 to 1.29)

  1. Legend; SD, standard deviation; MACR, modified alternate caloric restriction; CI, confidence interval; kg, kilogram; BMI, body mass index; ALT, alanine aminotransferase; AST, aspartate aminotransferase; TC, total cholesterol; LDL, low-density lipoprotein; HDL, high-density lipoprotein; TG, triglycerides; FBS, fasting blood sugar; SWE, shear wave elastography; kPa, kilopascal.
  2. *P value  < 0.05 was considered statistically significant aMean values for pre- and post-intervention for control and MACR group; bPaired t-tests; cIndependent t-tests.
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