Figure 2
From: Low immunogenic endothelial cells endothelialize the Left Ventricular Assist Device
EC reactivity is comparable between TCP and SIC. Semi-quantitative real-time RT-PCR was used to determine mRNA levels, normalized to β-actin. Analysis of the endothelial phenotype (FLT-1), endothelial specific activation (ICAM-1, VCAM-1, E-Selectin) and thrombogenic state markers (tissue factor, thrombomodulin) of ECs on TCPs and SICs, with and without TNFα-stimulation indicated a comparable preservation of the biological reactivity of the ECs. The paired two-tailed t-test was used to determine statistically significant differences (p < 0.05) indicated by the asterisks (*). Statistically insignificant results are marked by “ns”. The results are depicted as group means ± standard deviation (n = 3).
