Table 1 Clinical characteristics of the BASE-II study population according to T2D and sex.

From: Problematic drinking in the old and its association with muscle mass and muscle function in type II diabetes

 

Men (n = 714)

Women (n = 737)

p-valuea

p-valueb

no T2D (n = 598)

T2D (n = 116)

no T2D (n = 672)

T2D = (65)

Age [years]

69 ± 4

68 ± 4

68 ± 4

68 ± 3

0.105

0.368

BMI [kg/m²]

26.9 ± 3.3

29.5 ± 4.3

26.1 ± 4.4

30.2 ± 5.1

0.992

<0.001

Trunk fat [Kg]

13.7 ± 4.2

16.7 ± 4.9

13.4 ± 4.8

17.4 ± 4.6

0.692

<0.001

ALM [kg]

25.5 ± 3.0

26.0 ± 3.5

17.1 ± 2.4

17.9 ± 2.6

<0.001

0.003

Grip strength [kg]

42 ± 6.9

41.8 ± 7.7

26.5 ± 4.9

26.4 ± 5.8

<0.001

0.795

Alcohol intake

Problematic drinking (Audit > 5 in women or >8 in men) [n; %]

62 (10.4)

24 (20.7)

69 (10.3)

7 (10.8)

0.053

0.037

Alcohol Frequency (alcohol intake/week) [n; %]

Monthly or less

74 (12.4)

19 (16.4)

167 (24.9)

26 (40.0)

<0.001

0.129

2 to 4 times a month

112 (18.7)

23 (19.8)

218 (32.4)

12 (18.5)

2 to 3 times a week

170 (28.4)

26 (22.4)

148 (22.0)

15 (23.1)

4 or more times a week

242 (40.5)

48 (41.4)

139 (20.7)

12 (18.5)

Alcohol quantity (drinks/day) [n; %]

1 to 2

434 (72.6)

75 (64.7)

571 (85.0)

56 (86.2)

<0.001

0.577

3 to 4

137 (22.9)

38 (32.8)

94 (14.0)

8 (12.3)

5 to 6

19 (3.2)

1 (0.9)

6 (0.9)

1 (1.5)

7 to 9

4 (0.7)

2 (1.7)

1 (0.1)

0 (0.0)

10 or more

4 (0.7)

0 (0.0)

0 (0.0)

0 (0.0)

ALAT (U/L)

23 ± 10

31 ± 16

19 ± 8

24 ± 10

<0.001

<0.001

ASAT (U/L)

25 ± 6

28 ± 10

24 ± 6

25 ± 7

<0.001

<0.001

Gamma - GT (U/L)

34 ± 31

50 ± 71

23 ± 23

30 ± 18

<0.001

<0.001

HbA1c (%)

5.5 ± 0.4

6.6 ± 0.9

5.5 ± 0.3

6.4 ± 0.8

0.019

<0.001

TSH (mU/L)

2.1 ± 2.8

2.2 ± 3.0

2.3 ± 4.3

2.3 ± 3.5

0.544

0.844

CRP (mg/L)

1.8 ± 2.9

 ± 2.1 ± 2.2

2.1 ± 3.5

 ± 3 ± 2.9

0.018

0.025

CK (U/L)

123 ± 69

136 ± 96

101 ± 55

111 ± 61

<0.001

0.037

Testosterone (ng/mL)

4.8 ± 1.9

3.9 ± 1.8

0.2 ± 0.4

0.2 ± 0.1

<0.001

<0.001

Total energy intake (kcal/day)

2554.9 ± 702.4

2476.5 ± 756.8

1965.6 ± 546.7

1977.4 ± 638.6

<0.001

0.559

  1. Data are either mean ± SD or number (%). BMI = Body Mass Index; Trunk fat = trunk fat mass by DEXA; ALM = appendicular lean mass by DEXA; ALAT = Alanin-Aminotransferase; ASAT = Aspartat-Aminotransferase; CK = creatinine kinase; CRP = C-reactive protein; T2D = Diabetes mellitus type II.
  2. aStatistical significance by sex.
  3. bStatistical significance by T2D-status.
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