Figure 2 | Scientific Reports

Figure 2

From: High Glucose Environments Interfere with Bone Marrow-Derived Macrophage Inflammatory Mediator Release, the TLR4 Pathway and Glucose Metabolism

Figure 2

Hyperglycaemia promotes changes in BMDM phenotypes. (A) Expression of F4/80, CD11b, CD38 and CD206 before 24 hours of treatment and (B) CD38 and (C) CD206 expression, (D) arginase activity, and (E) CD80, (F) CD86 and (G) MHC-II expression after 24 hours of incubation in normal (5.5 mM) or high glucose (25 or 40 mM) with or without LPS. *p < 0.05 compared to normoglycaemic BMDMs, +<0.05 compared with control glucose medium. Data are presented as the means ± SEM (N = at least 3).

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