Table 1 Anti-ZIKV activity (EC50) and cytotoxicity (CC50) of statins in Vero cells. SI, selectivity index, CC50/EC50; NC, not calculated.
From: Lipophilic statins inhibit Zika virus production in Vero cells
Statin | EC50 (µM) | CC50 (µM) | SI |
|---|---|---|---|
Atorvastatin (ATO) | 7.34 | 24.31 | 3.31 |
Cerivastatin (CER) | 0.02 | 0.37 | 18.19 |
Fluvastatin (FLU) | 1.49 | 6.03 | 4.06 |
Lovastatin (LOV) | 14.59 | 38.76 | 2.66 |
Mevastatin (MEV) | 3.39 | 14.45 | 4.27 |
Simvastatin (SIM) | 2.55 | 7.14 | 2.81 |
Pravastatin (PRA) | NC | NC | NC |
Rosuvastatin (ROS) | NC | NC | NC |
