Figure 4
From: Therapeutic Effect of pHLIP-mediated CEACAM6 Gene Silencing in Lung Adenocarcinoma

Concurrent treatment with siCEACAM6 and cisplatin improves therapeutic responses. (a) Nude mice bearing A549 tumours were injected intravenously with pHLIP-siCEACAM6 or cisplatin at the indicated times (arrows), and tumour volumes were measured thereafter (n = 5 mice/group). (b) Representative images of tumours from nude mice at 3 weeks after injection of pHLIP-scr, pHLIP-siCEACAM6, cisplatin, or pHLIP-siCEACAM6 + cisplatin. Data are shown as mean ± s.d.; **P < 0.01; ***P < 0.001.