Table 3 Faecal calprotectin, faecal zonulin and serum LPS for patients with PPI-associated dysbiosis. Data is given as Median and 95% confidence interval.

N

32

18

50

Calprotectin (ng/mg)

271 (206–394)

59 (32–206)

17 (12–65)

^ap < 0.001, ^bp = 0.059, ^cp = 0.012

Zonulin (ng/mg)

85 (71–102)

83 (62–97)

69 (51–78)

^ap = 0.019, ^bp = 0.165, ^cp > 0.999

LPS (EU/ml)

3 (0–9)

0 (2–7)

0 (0–1)

^ap = 0.032, ^bp = 0.116, ^cp > 0.999

N

30

20

50

Calprotectin (ng/mg)

218 (167–348)

206 (48–318)

17 (12–65)

^ap < 0.001, ^bp < 0.001, ^cp = 0.961

Zonulin (ng/mg)

84 (65–100)

84 (71–102)

69 (51–78)

^ap = 0.035, ^bp = 0.074, ^cp > 0.999

LPS (EU/ml)

3 (1–12)

1 (0–7)

0 (0–1)

^ap = 0.009, ^bp = 0.333, ^cp > 0.999

N

31

19

50

Calprotectin (ng/mg)

270 (183–406)

167 (32–264)

17 (12–65)

^ap = 0.005, ^bp < 0.001, ^cp = 0.100

Zonulin (ng/mg)

90 (71–109)

83 (47–97)

69 (51–78)

^ap = 0.005, ^bp = 0.465, ^cp = 0.710

LPS (EU/ml)

2 (0–7)

3 (0–12)

0 (0–1)

^ap = 0.096, ^bp = 0.025, ^cp > 0.999