Figure 1

Tail suspension phenotype in wild type and H304R/R mutant mice. Left: The typical tail suspension reflex is hind limbs splaying away from the body. The atypical reflex is hind limbs clenching together closer to the body. Right: Male (A) and female (B) atypical tail suspension reflexes were scored per 3-month long time intervals and were statistically compared between the wild type and H304R/R mice using Fisher’s Exact test (two-tailed distribution, p < 0.05). The wild-type data was generated and previously reported in Sabblah et al.5.