Table 1 Demographic characteristics, echocardiographic parameter, operative characteristics of the study population.
From: Regulation of PDE5 expression in human aorta and thoracic aortic aneurysms
Variables | Marfan Syndrome (n = 7) | Tricuspid Valve (n = 19) | Bicuspid Valve (n = 12) | p-value |
|---|---|---|---|---|
BSA | 1.9 [1.2, 2.4] | 1.9 [1.5, 3.3] | 1.9 [1.5, 2.1] | 0,875 |
BMI | 21.9 (5)* | 28.5 (4.3)* | 25.8 (2.5) | 0,002 |
Age | 35.9 (14.5)* | 69.4 (10.5)* | 61 (12.9)* | <0.001 |
Gender M | 4 (57.1%) | 13 (68.4%) | 10 (83.3%) | 0,357 |
Hypertension | 5 (71.4%) | 13 (68.4%) | 10 (83.3%) | 0,628 |
Familiarity for cardiovascular diseases | 7 (100%) | 14 (73.6%) | 9 (75%) | 0,438 |
Echocardiographyc parameter | ||||
Aortic root | 50 [44, 55] | 47 [32, 53] | 44.5 [35, 50] | 0,078 |
Ascending aorta | 47.4 (6.8) | 50.4 (3.7) | 47.3 (4.8) | 0,152 |
Left ventricul telediastolic diameter | 51.4 (3.2) | 51.1 (4.8) | 50.8 (3.2) | 0,938 |
Left ventricul telesistolic diameter | 36 [33, 40] | 36 [24, 43] | 36 [28, 38] | 0,867 |
Septum | 11 [10, 12] | 11 [9, 14] | 12 [10, 16] | 0,221 |
Posterior wall | 11 (0.8) | 11.1 (1.7) | 12 (1.9) | 0,259 |
Left ventricul telediastolic volume | 96.9 (29.7) | 110.1 (20.3) | 100.9 (22.2) | 0,342 |
Left ventricul telesystolic volume | 53.1 (9.1) | 53.8 (9.4) | 47.7 (9.8) | 0,206 |
Ejection Fraction% | 55 [55, 70] | 55 [50, 60] | 58 [50, 60] | 0,885 |
Mitral regurgitation (I or II) | 5 (71.4%) | 15 (78.9%) | 6 (50%) | 0,269 |
Aortic stenosis | 0 (0%) | 2 (10.5%) | 6 (50%) | 0,017 |
Aortic regurgitation | 3 (42.8%) | 9 (47.3%) | 5 (41.6%) | 1,000 |
Systolic pulmonary arterial pressure | 29.1 (6.2) | 31.2 (6.8) | 31.1 (5.6) | 0,747 |
Operative characteristics | ||||
Procedure type | Â | Â | Â | 0,280 |
   Bental-De Bono | 7 (100%) | 14 (73.6%) | 11 (91.6%) |  |
   Ascending aorta replacement | 0 (0%) | 5 (26.3%) | 1 (8.3%) |  |
Associated procedures, yes | 2 (28.5%) | 5 (26.3%) | 1 (8.3%) | 0,498 |
Emergency | 0 (0%) | 1 (5.2%) | 2 (16.6%) | 0,568 |
Type of aortic prostheses | Â | Â | Â | 0,081 |
   mechanical | 7 (100%) | 10 (52.6%) | 7 (58.3%) |  |
   bioprosthesis | 0 (0%) | 9 (47.4%) | 5 (41.7%) |  |
Size of aortic prostheses | 23 [19, 25] | 23 [19, 27] | 23 [21, 25] | 0,878 |
Size of vascular prostheses | 25.9 (1.5) | 27.3 (1.9) | 26.7 (1.3) | 0,166 |
Cardioplegia | Â | Â | Â | 0,805 |
   Cristalloid | 7 (100%) | 16 (16%) | 11 (91.7%) |  |
   Ematic | 0 | 3 (15.7%) | 1 (8.3%) |  |
Surgery time | 310 [210, 800] | 240 [160, 540] | 232 [185, 393] | 0,093 |
Ejection Fraction % | 60 [35, 70] | 57 [40, 60] | 60 [42, 65] | 0,537 |
