Figure 5
From: Pathophysiologic Characterization of a Novel Rabbit Model of Biliary Tract Infection-Derived Sepsis

H&E staining of the liver tissue. 36 rabbits (6 rabbits per group) were subjected to cholecystocolonic anastomosis and liver tissue samples were harvested. The grade of cholangitis was found to be significantly increased over time (A). Data are presented as mean ± SD and compared using ordinary one-way analysis of variance and the Dunnett’s multiple comparisons test. P* < 0.05 vs group sham and group of the 12 h time point. H&E staining of the liver tissue at 12 h (C), 24 h (D), 48 h (E), and 72 h (F) time point after modeling versus sham group (B). The white arrows indicate a portion of inflammatory infiltration or purulence, the black arrows indicate hyperplasia of small bile ducts, and the white triangles indicate zone of extensive coagulative necrosis. (Original magnification: × 100 and × 400).