Figure 6
Impact of p21 on renal fibrosis progression. (a) Masson’s trichrome staining of tissues from WT and p21−/− mice. Upper panels are low magnifications (x200) and lower panels were high magnifications (x400). (b) Immunostaining staining of obstructed kidneys in WT and p21−/− mice. Scale bar, 100 µm. (c,d) The quantification of α-SMA (c) and E-Cadherin (d). N = 3 different mice for each time points in each genotypes. Data are as given averages ± SD; *P < 0.05; **P < 0.01. NS, Not Significant (two-tailed unpaired Student’s t-test). (e) Immunoblotting with indicted antibodies of tissue lysates from 7 days after the injury.
