Table 7 Number of micronucleus in polychromatic erythrocytes, dose-dependently.

From: Genotoxicity and glucose tolerance induction by acetyltriethylcitrate, substitute plasticizer compared to di(2-ethylhexyl)phthalate

Group

Dose (mg/kg)

PCE/(PCE + NCE)

MNPCE/PCE

Vehicle

0

0.341 ± 0.019

0.4 ± 0.7

DEHP

500

0.384 ± 0.052

0.4 ± 0.5

1000

0.381 ± 0.031

0.2 ± 0.4

2000

0.346 ± 0.029

0.4 ± 0.5

ATEC

500

0.379 ± 0.066

0.4 ± 0.5

1000

0.372 ± 0.051

1.0 ± 1.0

2000

0.326 ± 0.031

0.2 ± 0.4

MMC

2

0.348 ± 0.027

100 ± 7.35†,*

  1. MNPCE: Micronucleated polychromatic erythrocyte.
  2. PCE: Polychromatic erythrocyte.
  3. NCE: Normochromatic erythrocyte.
  4. MMC: Mitomycin C.
  5. Significant difference from negative control by Kastendaum & Bowman: †p < 0.05.
  6. Significant difference from negative control by Dunnett’s t-test: *p < 0.05.
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