Table 2 Factors Associated with Objective Response Rate.

From: Predictive and Prognostic Value of 18F-fluorodeoxyglucose Uptake Combined with Thymidylate Synthase Expression in Patients with Advanced Non-Small Cell Lung Cancer

 

Univariate

Multivariate

OR

95% CI

P-value

OR

95% CI

P-value

AP group (vs. GP group)

2.28

1.33–3.93

0.003

3.15

1.64–6.04

0.001

High TLG (vs. low TLG)

1.88

1.03–3.43

0.038

2.05

1.08–3.88

0.027

Male (vs. female)

0.56

0.33–0.96

0.034

0.44

0.23–0.83

0.011

EGFR wild-type (vs. mutation)

1.20

0.69–2.12

0.517

   

TS-positive (vs. TS-negative)

1.06

0.63–1.79

0.833

   

Ever smoked (vs. never smoker)

0.91

0.54–1.54

0.722

   

Age ≥65 years (vs. <65 years)

0.68

0.51–1.55

0.890

   

ALK rearrangement

1.18

0.39–3.53

0.764

   
  1. OR, odds ratio; CI, confidence interval; AP, pemetrexed/cisplatin-treated; GP, gemcitabine/cisplatin-treated; EGFR, epidermal growth factor receptor; TS, thymidylate synthase; ALK, anaplastic lymphoma kinase.
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