Figure 3

Repeated stress decreased firing rate and increased cyclicity of BA neurons in females. (A) Single BA neurons were recorded from male and female rats. (B) The firing rate of BA neurons was decreased after repeated stress in female rats, but was increased by repeated stress in male rats (left, mean + 95% C.I.; right, log10 transformed data mean ± s.e.m.). (C) The firing rate of BA neurons was greater in proestrus compared to diestrus in control rats and after repeated stress (left, mean + 95% C.I.; right, log10 transformed data mean ± s.e.m.). (D) This sensitivity to estrous was increased after repeated stress, reflected as increase in the cyclicity index after repeated stress (mean ± s.e.m.). *p < 0.05 Holm-Sidak’s multiple comparisons test after 2-way ANOVA.