Figure 7
Effects of repeated stress on conditioned fear. (A) Repeated stress did not significantly impact freezing during fear conditioning in males. (B) The initial expression of conditioned fear (trials 1–3) and the acquisition of extinction (trials 5–15) were both measured. Repeated stress increased the initial expression of conditioned fear in male rats (trials 1–3), but not the acquisition of extinction (trials 5–15). (C) Repeated stress did not significantly impact freezing during fear conditioning in females. (D) Repeated stress did increase the initial expression of conditioned fear in female rats (trials 1–3), but decreased the acquisition of extinction (trials 5–15). All data mean ± s.e.m. *p < 0.05 Holm-Sidak’s multiple comparisons test after 2-way ANOVA.
