Figure 2
From: Connective tissue growth factor is correlated with peritoneal lymphangiogenesis
Connective tissue growth factor (CTGF) expression was correlated with expression of lymphatic markers and vascular endothelial growth factor-C (VEGF-C) in human peritoneal biopsies. Human peritoneal biopsy specimens were collected from 32 uremic patients before initiation of peritoneal dialysis (PD), 23 patients undergoing PD not complicated by ultrafiltration failure (UFF), and seven PD patients with UFF. Quantitative polymerase chain reaction analysis showed positive correlations between CTGF messenger RNA (mRNA) expression and lymphatic vessel endothelial hyaluronan receptor-1 (LYVE-1) (a), podoplanin (b), and VEGF-C (c) mRNA expression in 62 human peritoneal biopsy samples. 18 S ribosomal RNA (rRNA) was used as an internal reference. Values were transformed into the logarithmic scale for Pearson correlation.
