Figure 2
From: Transcriptomic and functional analyses of 3D placental extravillous trophoblast spheroids
Transcriptome profiling of global gene expression changes in EVTs cultured as 3D spheroids compared to 2D monolayers. (a) Volcano plot comparing fold change (Log2) to p-value (-Log10) of differentially expressed genes measured using Clariom S Human microarray (Thermo). Significance determined by p < 0.05 and absolute fold change ≥2. (b) Dendrogram demonstrating clustering of the samples by similarity of transcriptome profiles. Four samples were analyzed per group, with different letters at the end of the name indicating a distinct sample.
