Table 4 Cox multivariate proportional hazard analysis according to GAP stage.

From: Prognosis of non-small-cell lung cancer in patients with idiopathic pulmonary fibrosis

Variables

GAP stage I

GAP stage II/III

HR

95% CI

P value

HR

95% CI

P value

Lung cancer stage

  

0.001

  

0.002

  Stage I

1.000

  

1.000

  

  Stage II

1.489

0.722–3.072

0.281

0.183

0.023–1.455

0.108

  Stage III

1.508

0.715–3.179

0.281

5.384

0.520–55.729

0.158

  Stage IV

7.775

2.593–23.307

<0.001

35.94

3.606–358.215

0.002

ECOG

  

0.077

  

0.007

  ECOG 0 and 1

1.000

  

1.000

  

  ECOG 2

1.134

0.471–2.732

0.779

3.71

1.436–9.587

0.007

  ECOG 3 and 4

3.037

1.152–8.010

0.025

4.711

1.558–14.240

0.006

Primary treatment

  

0.005

  

0.377

  Conservative care

1.000

  

1.000

  

  Operation

0.233

0.094–0.574

0.002

2.118

0.261–17.207

0.482

  Chemotherapy

0.613

0.210–1.787

0.370

0.818

0.296–2.265

0.700

  Radiotherapy

0.421

0.115–1.541

0.191

0.323

0.077–0.077

0.123

Total amount of cigarettes smoked in a lifetime (PYs)

0.993

0.982–1.004

0.189

1.016

1.002–1.031

0.031

  1. Abbreviations: HR = Hazard ratio, GAP = gender (G), age (A), and two physiology variables (P) (FVC and DLco)) stage system; PYs = pack-years; ECOG = Eastern Cooperative Oncology Group.
  2. *Adjusted for lung cancer clinical stage, ECOG, primary treatment, and smoking amount.