Table 2 R1 and R2 input and output panning metrics illustrating respective library enrichments and primary ELISA hit-rates for both TEM1-bio and TEM1-SpyC antigens.
Library | hTEM1-bio | hTEM1-SpyC | mTEM1-SpyC | ||||
|---|---|---|---|---|---|---|---|
λ | κ | λ | κ | λ | κ | ||
R1 | Input (phage; CFU) | 7.4 × 1012 | 5.3 × 1012 | 7.4 × 1012 | 5.3 × 1012 | 7.4 × 1012 | 5.3 × 1012 |
Output (CFU) | 1.4 × 106 | 1.1 × 106 | 5.6 × 105 | 6.3 × 105 | 4.4 × 105 | 3.2 × 105 | |
R2 | Input (phage; CFU) | 1.6 × 1011 | 1.2 × 1011 | 1.2 × 1011 | 1.4 × 1011 | 2.4 × 1011 | 1.9 × 1011 |
Output (CFU) | 2.3 × 109 | 1.7 × 109 | 3.0 × 109 | 2.6 × 109 | 5.3 × 109 | 4.1 × 109 | |
|  | Enrichment Factor* | 7.6 × 10 4 | 6.8 × 10 4 | 3.3 × 10 5 | 1.6 × 10 5 | 3.7 × 10 5 | 3.6 × 10 5 |
R2 | ELISA hit rate (%)‡ | 43 | 25 | 56 | 42 | 68 | 44 |
